From pfpc@istar.ca Fri Jan 19 18:10:50 2001 Date: Thu, 7 Dec 2000 01:02:52 -0800 From: Andreas Schuld To: webmaster@bruha.com Subject: PFPC:Fluorosis = Low T3 Hi all, QUOTE: "Hence, the syndrome of low T3 ...may be considered as diagnostic signs of fluorosis." [Note: "Low T3" syndrome is also referred to as "Wilson's Syndrome" in the US. The Wilson's Syndrome Foundation reports that almost 30% of the US population show symptoms consistent with WS = low T3 syndrome] SOURCE: Mikhailets ND, Balabolkin MI, Rakitin VA, Danilov IP - "Thyroid function during prolonged exposure to fluorides." Problemy Endokrinologii 42 (1):6-9 (1996) "Thyroid function was examined in 165 workers of electrolysis shops of aluminum production with more or less expressed signs of chronic fluoride intoxication (fluorosis) by radioimmunoassay of hormones and the test of 131I absorption by the thyroid. The detected thyroid abnormalities were characterized by a moderate reduction of iodine-absorbing function of the thyroid, low T3 with normal T4 level, and a slight increase of TTH concentration. These changes augmented with longer service and fluorosis progress. Hence, the syndrome of low T3 and reduced absorption of 131I may be considered as diagnostic signs of fluorosis. In case of toxic involvement of the liver in fluorosis patients, low T3 syndrome is observed much more frequently: in 75.6% cases. Liver abnormalities evidently lead to disorders in the peripheral conversion of T4 in T3, occurring primarily in liver parenchyma. Indirect effect of fluorine on the enzymatic system of deiodination cannot be ruled out as well." ==== NOTES: Over 60 years ago it was discovered that fluoride's actions as an anti-thyroid medication was due to its activity in the liver. When even slightly iodine-deficient, fluoride greatly ENHANCES uptake of I131. Fluoride, as a TSH clone, is a direct antagonist of Free T3. Andreas