From pfpc@istar.ca Thu May 4 10:33:07 2000 Date: Sun, 30 Apr 2000 16:56:05 -0800 In the Ukrainian town of Sosnivka, near Lviv, drinking water is polluted with fluoride. A governmental commission had been established to investigate the situation. The commission found that there were three possible sources of the pollution: the activity of a nearby coal mining company, the underground storage of rocket fuel by a former military base that had been closed in 1990, or a "natural phenomenon". The NGO Ecopravo-Lviv attempted to bring a case to arbitration court on behalf of mothers whose children suffered from this fluoride pollution of drinking water. The state duty for the case, which totaled GRV 9,000 (about US$ 4,500), made access to justice unaffordable. According to the Arbitration Procedure Code, it is impossible to waive payment of state duty even for an NGO that is trying to defend environmental rights of citizens. As a result, the number of severely sick children has grown from 600 to about 3,000, and the pollution and aggravation of diseases has also increased. Because the community cannot afford to carry out adequate scientific analysis and the government has failed to monitor local industrial plants, this important case has now foundered. When studies are done on endemic fluorosis regions, it is almost never specified as to how these " high fluoride levels" occur. Presumed to be "natural"... STRUCTURAL-FUNCTIONAL STATE OF BONE IN THE WOMEN OF DIFFERENT AGE RESIDING IN THE ENDEMIC REGIONS WITH HIGH WATER FLUORIDE CONTENT 1Vladislav Povoroznjuk, 2Teofil Pidlesetsky 1Institute of Gerontology AMS of Ukraine, 2Medical University, Lviv, Vyshgorodskaya St. 67, 254114, Kyiv, Ukraine Effects of an increased water fluoride content on the bone tissue, the rate of its aging and the prevalence of osteoporosis were studied in 109 women (gr. 1) aged 20- 69 years residing in the areas of Lviv Region with a high fluoride content of drinking water. The control subjects (gr. 2) included women of the same age from the areas in which there was a normal water fluoride content, standardized according to the body mass index and peculiarities of nutrition. The bone tissue was examined using an ultrasound densitometer "Achilles+" (Lunar Corp.). The speed of the sound (SOS, m/s), broadband ultrasound attenuation (BUA, dB/MHz) and an estimated "stiffness" index (SI, %) were measured. The results of the studies show the negative influence of the high fluoride content in the drinking water on the structural-functional bone tissue state, that leads to the accelerated aging, decrease of the bone density characteristics, development of osteoporosis. The female population of age groups of 20- 29 years (the period of bone peak formation) and 50- 59 years (postmenopausal period) turned out to be the most sensitive. In the 1stgroup's women, there was a significant decrease in SOS, BUA and SI (20- 29 yrs - 1550±5,8 m/s, 105,4±2,62 dB/MHz and 85,2±3,3%; 50- 59 yrs - 1521±6,8 m/s, 98,2±2,65 dB/MHz and 71,2±3,8%) in comparison with control group (20- 29 yrs - 1592±6,5 m/s, 119,2±3,31 dB/MHz and 92,4±1,6%; 50- 59 yrs - 1552±5,8 m/s, 106,1±2,51dB/MHz and 83,8±2,3%) The essential difference between indexes characterizing bone tissue state among the age groups of 30- 39 years and 40- 49 years weren't revealed. Structural-functional age of bone tissue in the 1st group's women exceeded the population standard among the age groups of 20- 29 years (by 5,8 years) and 50- 59 years (by 6,3 years). Among the group aged 50- 59 years in the women 1st group osteoporosis was revealed in 26,3%, osteopenia - in 63,2%, while among the women of 2 group with the appropriate age osteoporosis was revealed only in 12,5%, osteopenia - in 35,4%. In summary, the high fluoride content of drinking water promote the worsening of structural-functional bone tissue state among the women during the period of bone peak formation and the postmenopausal period. ---- Wendy Small